CU Startup News

A simple shot shows promise to reverse osteoarthritis within weeks

Daniel Corbin Leonard — Mon, 06 Apr 2026 21:10:40 +0000

A simple shot shows promise to reverse osteoarthritis within weeks Daniel Corbin … Mon, 04/06/2026 - 15:10

A research team including scientists and engineers from the University of Colorado Boulder, University of Colorado Anschutz and Colorado State University has developed a suite of new therapies that prompt aging or damaged joints to repair themselves within weeks, according to animal studies.

The new osteoarthritis treatments include a single, regenerative injection to a joint and a biomaterial repair kit that recruits the body’s own cells to patch holes in damaged cartilage.

To expedite the research, the federal Advanced Research Projects Agency for Health (ARPA-H) announced this week that the multidisciplinary team will advance to the next phase of the up to $33.5 million project. The project is under the ARPA-H Novel Innovations for Tissue Regeneration in Osteoarthritis (NITRO) program. NITRO is led by ARPA-H Program Manager Dr. Ross Uhrich.

“In two years, we were able to go from a moonshot idea to developing these therapies to demonstrating that they reverse osteoarthritis in animals,” said principal investigator Stephanie Bryant, professor of chemical and biological engineering at �鶹��Ƶ. “Our goal is not just to treat pain and halt progression, but to end this disease.”

The team hopes to publish their animal findings in a peer reviewed journal later this year and has formed a company, Renovare Therapeutics Inc. to move toward commercialization.

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The New York Times, �鶹��Ƶ Today—A research team of scientists and engineers from the University of Colorado Boulder, University of Colorado Anschutz Medical Campus and Colorado State University has developed a suite of therapies that prompt aging or damaged joints to repair themselves within weeks, according to animal studies. The Advanced Research Projects Agency for Health (ARPA-H) has advanced the up to $33.5M project to its next phase, and the team has formed Renovare Therapeutics Inc. to move toward commercialization.

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�鶹��Ƶ and Techstars announce partnership to accelerate Colorado’s entrepreneurial ecosystem

Daniel Corbin Leonard — Thu, 02 Apr 2026 19:19:02 +0000

�鶹��Ƶ and Techstars announce partnership to accelerate Colorado’s entrepreneurial ecosystem Daniel Corbin … Thu, 04/02/2026 - 13:19

Daniel Leonard

The University of Colorado Boulder and Techstars, the global startup accelerator and investor, have announced a strategic partnership to expand opportunities for founders and strengthen Colorado’s innovation economy.

The collaboration connects �鶹��Ƶ’s entrepreneurship programs and startup pipeline with Techstars’ network of mentors, investors and partners—creating new pathways for innovators to build and scale companies that drive real-world impact.

“This partnership reflects �鶹��Ƶ’s commitment to empowering people across our campus to turn ideas into impact,” said Massimo Ruzzene, senior vice chancellor for research and innovation and dean of the institutes. “Our students, faculty and researchers are developing technologies, launching companies and exploring solutions to real challenges. Working with Techstars connects that talent with a global community of entrepreneurs and investors who can help move those ideas from campus into the world.”

From discovery to startup

�鶹��Ƶ has emerged as one of the most vibrant startup ecosystems on a university campus in the United States. Through research, entrepreneurial education and the campus-wide Innovation & Entrepreneurship Initiative, the university supports students and faculty pursuing new ventures based on breakthrough discoveries.

Venture Partners at �鶹��Ƶ—the university’s commercialization arm—has played a central role in that momentum and in initiating the new partnership. Through Venture Partners, more than 220 companies based on �鶹��Ƶ technologies have launched and collectively exited for over $11 billion. The campus was ranked first in the nation for the number of such startups launched in 2024, the second-most ever launched by a single university campus in one year.

The partnership with Techstars will connect �鶹��Ƶ’s innovations and entrepreneurs with one of the world’s premier startup accelerators and investors.

Established in Boulder in 2006 by David Cohen, Brad Feld, David Brown and Jared Polis, Techstars helped shape the city’s startup culture. What began as a single accelerator program has grown into a global platform supporting founders across industries and geographies.

“Techstars has operated continuously in Colorado for two decades. The re-launch of our Techstars Boulder accelerator here reflects our renewed commitment to Colorado and reinforces Boulder’s role as an important hub in our system,” said David Cohen, chief executive officer of Techstars and co-founder of the company. “�鶹��Ƶ is a powerful source of new ideas and new companies. By building a deeper relationship with the university, we can help more founders turn breakthroughs into companies that scale.”

Today, Techstars has invested in thousands of startups worldwide, whose combined market value exceeds $220 billion.

�鶹��Ƶ and Techstars count dozens of unicorns between them, including DigitalOcean, SendGrid, Salesloft, and Veho (Techstars), Infleqtion, Ball Aerospace & Technologies, Solid Power and SomaLogic (�鶹��Ƶ).

Expanding pathways for founders

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�鶹��Ƶ’s students and faculty will engage with Techstars staff, mentors and alumni through university entrepreneurship programs such as the New Venture Challenge and Embark Deep Tech Startup Creator. The collaboration will also create opportunities for Techstars founders to work with �鶹��Ƶ researchers and students while accessing specialized facilities and technical expertise.

For startups emerging from the university, the partnership opens a direct pathway to Techstars’ accelerator programs and investor network.

“This collaboration brings together two communities deeply committed to building great companies,” said Shay Har-Noy, managing director of Techstars Boulder. “�鶹��Ƶ consistently produces exceptional research, founders and high-potential companies. By working closely, we can help even more of these teams scale into enduring, world-class businesses.”

“Techstars Boulder just opened applications for its first new cohort, kicking off in person this September,” said Har-Noy, “We’re passionate about backing the strongest founders and companies from �鶹��Ƶ, across Colorado and from around the country.”

Strengthening Colorado’s innovation economy

The partnership strengthens the connection between �鶹��Ƶ’s research and academic mission and the global startup community while expanding opportunities for founders emerging from the university.

“Boulder has long been a catalyst where research, entrepreneurship and community come together to improve people’s lives,” said Bryn Rees, senior associate vice chancellor for innovation and partnerships at �鶹��Ƶ. “This partnership with Techstars builds on that foundation. Together, we can help more great ideas become companies and more founders bring transformative ideas to the world.”

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Venture capitalists remain staunch believers that vaccines will pay off

Daniel Corbin Leonard — Thu, 02 Apr 2026 15:31:56 +0000

Venture capitalists remain staunch believers that vaccines will pay off Daniel Corbin … Thu, 04/02/2026 - 09:31

Wall Street Journal—The second Trump administration’s “Make America Healthy Again” movement targets vaccines, leading some investors to step back. In biotech investment circles, they are the ultimate contrarians: the venture capitalists who say now is the time to invest in vaccines. VitriVax, a �鶹��Ƶ spinout, raised more than $17.2 million in Series B financing in October.

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Two �鶹��Ƶ startups selected for Luminate New York Accelerator

Daniel Corbin Leonard — Fri, 20 Mar 2026 21:35:45 +0000

Two �鶹��Ƶ startups selected for Luminate New York Accelerator Daniel Corbin … Fri, 03/20/2026 - 15:35

Empire State Development (ESD) announced the 10 startups chosen for round nine of the New York State-supported Luminate NY accelerator, investment fund and competition—two are �鶹��Ƶ startups.

Selected by a panel of industry experts for their transformative work in OPI-enabled technologies, these startups were identified from a pool of 138 applicants from 33 different countries. The 2026 cohort will begin their time in Rochester on April 13, utilizing an initial $100,000 investment to continue to scale their businesses, leveraging New York’s ecosystem. At the accelerator graduation on September 30, they will vie for up to $2 million in follow-on funding to help commercialize their next-generation manufacturing, medical, and sensing solutions.

Manifest Technologies is solving the problems holding advanced manufacturing back through Parallax Volumetric Additive Manufacturing, a breakthrough platform that fabricates complex parts in a single, continuous step.

Modendo offers ultrathin microscopes that comprise a single optical fiber and provide high-resolution imaging for industrial and medical applications.

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Venture Partners at �鶹��Ƶ has helped faculty, students, researchers and entrepreneurs build over 220 new ventures based on technology and innovation from �鶹��Ƶ, UCCS and CU Denver. Explore some of our startups and investment opportunities.

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Luminate—Empire State Development (ESD) announced the 10 startups chosen for round nine of the New York State-supported Luminate NY accelerator, investment fund and competition—two are �鶹��Ƶ startups.

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Artimus Robotics is launching next-generation artificial muscles and seeking partners

Daniel Corbin Leonard — Tue, 17 Feb 2026 17:37:40 +0000

Artimus Robotics is launching next-generation artificial muscles and seeking partners Daniel Corbin … Tue, 02/17/2026 - 10:37

PR Newswire—Artimus Robotics, a �鶹��Ƶ spinout, has announced its newest generation of contracting HASEL actuators that deliver more than twice the mechanical output performance of the previous generation. Artimus, a �鶹��Ƶ spinout, is now one step closer to commercializing artificial muscles that replicate the performance of mammalian skeletal muscle.

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The University of Colorado Ascent Deep Tech Accelerator announces 2026 cohort

Daniel Corbin Leonard — Thu, 12 Feb 2026 18:35:39 +0000

The University of Colorado Ascent Deep Tech Accelerator announces 2026 cohort Daniel Corbin … Thu, 02/12/2026 - 11:35

Ascent Deep Tech Community Showcase

Attendees will have a chance to see pitches from each of the Ascent 2025 cohort startups, followed by a networking happy hour to learn more.

Wednesday, June 24, 2026, 4:30-7:30 p.m., Byron R. White Stadium Club, Folsom Field

The University of Colorado's Ascent Deep Tech Accelerator has announced its 2026 startup teams. The selected companies span a wide range of disciplines, reflecting the depth and breadth of innovation emerging from CU’s research enterprise.

Launched in 2021 by Venture Partners at �鶹��Ƶ, the Ascent Deep Tech Accelerator addresses the unique challenges faced by deep tech startups (companies based on groundbreaking science or engineering) that often require substantial time, research and capital to reach the market. The five-month program builds upon prerequisite customer-discovery training through the National Science Foundation (NSF) I-Corps^TM Hub West —also offered through Venture Partners—and provides tailored support in business formation, market strategy and fundraising.

Now in its fifth year, Ascent has announced its largest cohorts to date. The 2026 cohort includes startups tackling critical challenges in physical and life sciences, from hydrogen-powered energy systems and wildfire detection to regenerative medicine, advanced materials and next-generation robotics.

Since its inception, Ascent has graduated 47 companies, which collectively have raised more than $20 million in non-dilutive grants and $47 million in seed funding from venture capital investors. Alumni have gone on to secure spots in nationally recognized incubators such as NREL’s West Gate, Creative Destruction Lab, Techstars and Activate, further validating the program’s role in accelerating CU startups toward commercial success.

2026 Ascent Cohort

Agami Zero

Agami Zero Inc. develops hydrogen-powered, off-grid EV fast charging and clean power systems for grid-constrained and remote locations. Leveraging CU-licensed electrolysis technology, Agami Zero enables reliable EV charging and energy access without requiring utility upgrades, using cost-effective green hydrogen. Visit the Agami Zero Website

Team Members: Jafar Makrani, Co-Founder, CEO, jafar.makrani@agamizero.com*; Lyle Antieau, Co-Founder, CTO

Industry Applications: Environment and Sustainability, Cleantech, Hardware and Instrumentation

Arkana Therapeutics

Arkana Therapeutics leverages animals with extreme physiology to discover novel therapeutic molecules and drug targets.

Team Members: Jack Gugel, Co-Founder, CEO, jack@arkanatx.com*; Thomas Martin, Co-Founder, CSO; Jonathan Long (Stanford Medicine), Co-Founder, Scientific Advisor; Leslie Leinwand (�鶹��Ƶ Molecular, Cellular & Developmental Biology, BioFrontiers Institute), Scientific Advisor

Industry Applications: Biotech

BioStamp

BioStamp synthesizes DNA barcodes for engineered microorganisms, enabling biological intellectual property protection, compliance and high-fidelity identification. BioStamp's technology reduces detection false positives and collision probability through deterministic sequences, improving upon core limitations of random barcoding.

Team Members: John Docter (�鶹��Ƶ Environmental Engineering Program), Co-Founder, CEO, john.docter@colorado.edu*; Cresten Mansfeldt (�鶹��Ƶ Civil, Environmental and Architectural Engineering), Co-Founder, CSO

Industry Applications: Environment and Sustainability, Biotech, Genomics, Research and Exploration

BoBoRobo

BoBoRobo (Boulder-Born Robotics) automates the design, validation and deployment of industrial robotic workcells from a simple English prompt, cutting integration costs by 50% and time-to-live from six months to 10 days. Visit the BoBoRobo Website

Team Members: Alessandro Roncone (�鶹��Ƶ Computer Science), Co-Founder, CEO; Anuj Pasricha (Alum: �鶹��Ƶ Computer Science), Co-Founder, CTO, anuj.pasricha@colorado.edu*

Industry Applications: Robotics

Enlixa Bio

Enlixa Bio helps biopharma precisely drug the “undruggable” world of transcription by turning complex transcriptional machinery into actionable, tractable targets.

Team Members: Nik Chopra (�鶹��Ƶ Embark Startup Founder), Co-Founder, CEO, chopranik@gmail.com*; Elie Maksoud (�鶹��Ƶ Embark Startup Founder), Co-Founder, CTO

Industry Applications: Biotech, Genomics, Diagnostics

Flari Tech

Flari Tech Inc. is building a breath analysis platform powered by the 2005 Nobel Prize-winning optical frequency comb technology, based on cutting-edge innovations from Jun Ye's lab at JILA. Flari Tech aims to provide affordable, accessible disease detection solutions by revolutionizing breath diagnostics with quantum sensing. Visit the Flari Tech Website

Team Member: Eva Yao, Founder, CEO, info@flaritech.com*

Industry Applications: Medical Devices, Diagnostics

FlowPoint Bio

FlowPoint Bio is redefining cell engineering with its high-viability, continuous-flow microfluidic platform that enables delivery of gene-editing payloads directly into the nucleus, regardless of cell type or payload size. Visit the FlowPoint Bio Website

Team Members: Vineet Erasala, Co-Founder, CEO, vineet@flowpoint.bio*; Xiaoyun Ding (�鶹��Ƶ Paul M. Rady Mechanical Engineering), Co-Founder, Scientific Advisor

Industry Applications: Biotech, Manufacturing

iMembrane Therapeutics

iMembrane Therapeutics develops AI-designed miniproteins that overcome limitations of conventional biologics. The iMembrane Therapeutics platform enables stable, tunable and precisely dosed cytokine modulators for treating severe inflammatory diseases such as sepsis.

Team Members: Jingshi Shen, Co-Founder, CSO; Suzhao Li, sli@imembranetherapeutics.com*, Co-Founder, CEO; Charles Dinarello, Advisor

Industry Applications: Therapeutics

LeTau Robotics

LeTau Robotics develops AI foundation models to teach robots human-like dexterity with 100x less training data. LeTau Robotics enables rapid deployment (hours vs. months) for complex manipulation across manufacturing, logistics and labs—at a fraction of traditional costs.

Team Members: Zhengxiong Li (CU Denver Computer Science and Engineering), CEO, Co-Founder, zhengxiong.li@ucdenver.edu*; Lingfeng Tao, Co-Founder, Advisor; Xinmin Fang (Student: CU Denver Engineering, Design and Computing), Co-Founder, Advisor; Fenglong Ma, Co-Founder, CTO

Industry Applications: Artificial Intelligence (AI) and Machine Learning, Robotics

PEGI LLC

Peroxide Enhanced Germicidal Irradiation (PEGI) rapidly inactivates microbes, allergens and volatile organic compounds in HVAC systems, keeping coils clean between seasonal maintenance. PEGI boosts energy efficiency, extends system life, improves indoor air quality, and is easily retrofitted into existing commercial and residential systems.

Team Members: Emma Biesiada (�鶹��Ƶ Aerobiology and Disinfection Lab), Founder, CTO, emmalee.biesiada@gmail.com*; Mark Hernandez (�鶹��Ƶ Environmental Engineering Program), Advisor

Industry Applications: Environment and Sustainability, Cleantech, Medical Devices

Renovare Therapeutics

Renovare Therapeutics Inc. is developing regenerative therapeutics for osteoarthritis (OA). The Renovare Therapeutics portfolio of products can be customized to meet OA patients where they are, enabled through technologies including innovative biomaterials, gene therapies and controlled delivery of drugs and biologics that regenerate joint tissues.

Team Members: Stephanie Bryant (�鶹��Ƶ Chemical and Biological Engineering), Founder; Liz Scott, Fractional-CEO, elizabeth.scott-2@colorado.edu*; Karin Payne, Co-Principal Investigator (PI); Laurie Goodrich, Co-PI; Kelly Santagelo, Senior Investigator; Mike Zuscik, Co-PI

Industry Applications: Advanced Materials, Biotech, Therapeutics

RipaLith

RipaLith is based on the research by Mija Hubler (�鶹��Ƶ Civil, Environmental and Architectural Engineering), an expert in concrete degradation and structural performance. RipaLith is developing a concrete preservation solution that can be applied to existing concrete infrastructure to repair cracks—extending lifespan without costly replacement.

Team Members: Mija Hubler (�鶹��Ƶ Civil, Environmental and Architectural Engineering), Co-Founder, Engineering Advisor; Elena Forchielli (Embark Startup Founder), Co-Founder, CEO, elena.forchielli@colorado.edu*; Paolo Forchielli, Co-Founder, COO;

Industry Applications: Advanced Materials, Construction, Biotech

NITRO mBMAT

A collaboration between �鶹��Ƶ, AMC and Colorado State University, developing therapeutics to regenerate cartilage and bone in osteoarthritis. Founded by Stephanie Bryant, principal investigator (PI), they have $40 million in non-dilutive funding from ARPA-H and are raising funds to support IND-enabling studies and commercial plans.

Team Members: Liz Scott, CEO, elizabeth.scott-2@colorado.edu*; Stephanie Bryant (�鶹��Ƶ Chemical and Biological Engineering), Founder, CSO; Karin Payne, Co-Principal Investigator; Kelly Santangelo, Senior Investigator

Industry Applications: Biotech, Therapeutics

SureFire

SureFire employs breakthrough LLM and quantum information techniques to more quickly and accurately detect wildfire ignitions from existing thermal camera images. SureFire is launching solutions for fire detection and risk management for customers such as fire agencies, power utilities, insurance companies, and sensor vendors.

Team Members: Gary Robert Dolsen (�鶹��Ƶ Embark Startup Founder), Co-Founder, CEO, garydolsen@gmail.com*; Longji Cui (�鶹��Ƶ Paul M. Rady Mechanical Engineering), Co-Founder, CSO, Principal Investigator (PI); Kyle Kuczun, Co-Founder, CTO, CPO;

Industry Applications: Environment and Sustainability, Sensors, Software

Synteric Robotics

Synteric Robotics builds small, autonomous insect-inspired inspection robots designed to navigate tight, hazardous environments. Our technology combines novel micromechanics, sensing and autonomy to inspect infrastructure humans can’t easily reach.

Team Members: Rob Carpenter (�鶹��Ƶ Embark Startup Founder), Founder, rob@frostrivercapital.com*

Industry Applications: Artificial Intelligence (AI) and Machine Learning, Robotics

VeriLocal

VeriLocal Inc. is an AI platform that filters out non-local social media noise during fast-moving events. Using machine learning to identify geographically authentic content, it delivers real-time, high-signal local insight for crisis response, utilities, insurance, media and other decision-makers. Visit the VeriLocal Website

Team Members: Todd McGuire (�鶹��Ƶ Embark Startup Founder), Co-Founder, CEO, todd@verilocal.ai*; Lise St. Denis (Earth Lab), Co-Founder, CSO

Industry Applications: Information Technology, Software, Smart Cities

VersaMesh

VersaMesh develops software-designed, 3D-printed impact-absorbing metamaterials that outperform traditional foams. Our precisely tuned materials protect against repetitive low-energy hits and high-impact forces, enabling safer, customizable protection for helmets and other impact-critical applications.

Team Members: Teri Ham (�鶹��Ƶ Embark Startup Founder), Co-Founder, CEO, hamteri@gmail.com*; Renee Sanchez (�鶹��Ƶ Embark Startup Founder), Co-Founder, COO; Sloan Le, CTO

Industry Applications: Advanced Materials, Software, Additive Manufacturing

YarraBio

Yarrabio develops technologies for cancer research, drug discovery and clinical oncology.

Team Members: Savanh Chantha-Phavong (�鶹��Ƶ Embark Startup Founder), Co-Founder, CEO, CSO, savanh.c@yarrabio.com*; Corey Neu, Co-Founder, Scientific Advisor, Principal Investigator (PI)

Industry Applications: Biotech

*Team's primary point of contact for inquiries.

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Destination Startup announces startups across the region to present at annual showcase

Daniel Corbin Leonard — Thu, 29 Jan 2026 23:33:20 +0000

Destination Startup announces startups across the region to present at annual showcase Daniel Corbin … Thu, 01/29/2026 - 16:33

Destination Startup brings groundbreaking startups built on novel discoveries from top national labs and universities together with investors from throughout North America to catalyze real-world impact. This showcase demonstrates a powerful way to invest in and get funding for innovative research and translate it into impactful business ventures.

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Thermonat makes nanoscale thermal prediction practical for real-world chip design

Daniel Corbin Leonard — Tue, 20 Jan 2026 19:55:55 +0000

Thermonat makes nanoscale thermal prediction practical for real-world chip design Daniel Corbin … Tue, 01/20/2026 - 12:55

DARPA—One research team, led by the University of Colorado Boulder, formed a startup, AtomTCAD Inc., to bring its high-accuracy thermal modeling tools directly to semiconductor designers. The newly formed company has received funding from the Colorado Office of Economic Development & International Trade, and all four members of AtomTCAD’s research team received fellowships through �鶹��Ƶ’s Ascent Deep Tech Accelerator.

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Think Bioscience raises $55M in oversubscribed Series A

Daniel Corbin Leonard — Tue, 20 Jan 2026 17:55:27 +0000

Think Bioscience raises $55M in oversubscribed Series A Daniel Corbin … Tue, 01/20/2026 - 10:55

PR Newswire—Think Bioscience, a �鶹��Ƶ biotechnology spinout focused on unlocking elusive drug targets, has raised $55M in an oversubscribed Series A. Returning investors include AV8 Ventures, CU Innovations and Buff Gold Ventures.

The University of Colorado Connection

Think Bioscience is a Boulder-based synthetic biology company with strong roots at �鶹��Ƶ. The company was spun out of Jerome Fox's lab (�鶹��Ƶ Department of Chemical and Biological Engineering and BioFrontiers Institute), where its foundational technology, leveraging microbial systems to discover small-molecule drugs for previously “undruggable” targets, was developed. Its lead programs, including inhibitors of PTP1B, emerged directly from this academic research.

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Tech company makes breakthrough discovery that could boost EV performance

Daniel Corbin Leonard — Sat, 10 Jan 2026 17:26:36 +0000

Tech company makes breakthrough discovery that could boost EV performance Daniel Corbin … Sat, 01/10/2026 - 10:26

The Cool Down—Electric vehicles are getting closer to overcoming some of their biggest challenges, and a new battery breakthrough could play a major role in making EVs more practical and appealing for drivers. Porsche-backed Group14 Technologies and New York-based Sionic Energy, a �鶹��Ƶ spinout, recently announced a major breakthrough in lithium-ion battery technology that could significantly improve EV performance.

More at The Cool Down More from Sionic Energy

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